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Michael Fromm Selected Research

Tight Junction Proteins

1/2022MarvelD3 Is Upregulated in Ulcerative Colitis and Has Attenuating Effects during Colitis Indirectly Stabilizing the Intestinal Barrier.
3/2021Expression of tricellular tight junction proteins and the paracellular macromolecule barrier are recovered in remission of ulcerative colitis.
1/2019Tissue plasminogen activator and neuropathy open the blood-nerve barrier with upregulation of microRNA-155-5p in male rats.
1/2017Active and passive involvement of claudins in the pathophysiology of intestinal inflammatory diseases.
10/2009Inflamed pouch mucosa possesses altered tight junctions indicating recurrence of inflammatory bowel disease.
9/2009Arcobacter butzleri induces barrier dysfunction in intestinal HT-29/B6 cells.
5/2009Epithelial tight junctions in intestinal inflammation.
3/2007Effect of chronic Giardia lamblia infection on epithelial transport and barrier function in human duodenum.

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Michael Fromm Research Topics

Disease

16Inflammation (Inflammations)
01/2019 - 08/2006
14Diarrhea
04/2020 - 06/2004
10Ulcerative Colitis
01/2022 - 06/2004
9Infections
04/2020 - 05/2002
7Dehydration (Water Stress)
01/2022 - 11/2009
6Inflammatory Bowel Diseases (Inflammatory Bowel Disease)
01/2022 - 01/2009
6Crohn Disease (Crohn's Disease)
10/2020 - 08/2005
5Colitis
01/2022 - 12/2014
5Necrosis
12/2017 - 05/2002
4Neoplasms (Cancer)
06/2020 - 04/2012
3Celiac Disease (Celiac Sprue)
03/2017 - 07/2012
3Glaucoma
02/2011 - 07/2005
3Pouchitis
10/2009 - 08/2006
2Cataract (Cataracts)
04/2022 - 11/2008
2Moyamoya Disease (Moya-Moya Disease)
11/2018 - 04/2017
2Lymphocytic Colitis
10/2017 - 07/2012
2Intestinal Diseases (Diseases, Intestinal)
05/2017 - 06/2015
2Hyperplasia
03/2017 - 01/2012
2Atrophy
03/2017 - 07/2012
2Microscopic Colitis
01/2017 - 06/2015
2HIV Enteropathy
06/2015 - 05/2002
2Collagenous Colitis
07/2012 - 08/2002
2Open-Angle Glaucoma (Glaucoma, Open Angle)
02/2011 - 10/2007
1Herpes Zoster
01/2019
1Hyperalgesia
01/2019
1Foodborne Diseases
12/2017
1Cerebrovascular Disorders (Cerebrovascular Occlusion)
04/2017
1Gallstones (Gallstone)
06/2015
1Communicable Diseases (Infectious Diseases)
06/2015
1Irritable Bowel Syndrome (Syndrome, Irritable Bowel)
06/2015
1Clostridium Infections
06/2015
1Pain (Aches)
06/2012
1Wounds and Injuries (Trauma)
10/2011
1Arthritis (Polyarthritis)
02/2011

Drug/Important Bio-Agent (IBA)

11Proteins (Proteins, Gene)FDA Link
06/2020 - 06/2008
10CytokinesIBA
10/2017 - 05/2002
8Tight Junction ProteinsIBA
01/2022 - 03/2007
7AntigensIBA
03/2021 - 08/2006
6Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA
01/2017 - 05/2002
5Interleukin-13IBA
01/2022 - 08/2005
5ClaudinsIBA
12/2017 - 03/2011
5SodiumIBA
01/2017 - 06/2004
4Claudin-4IBA
10/2017 - 06/2008
4ChloridesIBA
10/2011 - 08/2002
3Claudin-2IBA
01/2017 - 05/2009
3Glucose (Dextrose)FDA LinkGeneric
01/2015 - 08/2006
3ChromatinIBA
07/2014 - 11/2010
3Histones (Histone)IBA
03/2014 - 11/2010
3histone H3 trimethyl Lys4IBA
03/2014 - 11/2010
3Interferon-gamma (Interferon, gamma)IBA
05/2009 - 05/2002
2Phenobarbital (Luminal)FDA Link
03/2021 - 05/2009
2Anti-Bacterial Agents (Antibiotics)IBA
11/2019 - 12/2017
2Claudin-5IBA
10/2017 - 01/2017
2Glutens (Glutelin)IBA
03/2017 - 07/2012
2Biological ProductsIBA
01/2015 - 12/2013
2Abscisic AcidIBA
07/2014 - 06/2011
2Endothelins (Endothelin)IBA
02/2011 - 03/2006
2Nucleosomes (Nucleosome)IBA
11/2010 - 01/2005
2Endothelin-1 (Endothelin 1)IBA
10/2007 - 07/2005
2Mannitol (Osmitrol)FDA LinkGeneric
03/2007 - 08/2006
1Dextrans (Dextran)FDA Link
01/2022
1CationsIBA
01/2022
1sodium sulfate (sodium bisulfate)FDA LinkGeneric
01/2022
1LeptinIBA
10/2020
1ZincIBA
04/2020
1Hemolysin Proteins (Hemolysins)IBA
04/2020
1MARVEL Domain Containing 2 ProteinIBA
11/2019
1VaccinesIBA
08/2019
1Messenger RNA (mRNA)IBA
01/2019
1Matrix Metalloproteinase 9 (Gelatinase B)IBA
11/2018
1Clostridium enterotoxinIBA
12/2017
1OxazoloneIBA
05/2017
1myrrh resin (myrrh)IBA
05/2017
1Angiopoietin-2IBA
04/2017
1claudin 8IBA
01/2017
1p38 Mitogen-Activated Protein KinasesIBA
12/2015
1Fatty Acids (Saturated Fatty Acids)IBA
01/2015
1Virulence Factors (Pathogenicity Factors)IBA
12/2014
1Protein Kinases (Protein Kinase)IBA
07/2014
1Transcription Factors (Transcription Factor)IBA
07/2014
1Hormones (Hormone)IBA
12/2013
1RNA (Ribonucleic Acid)IBA
12/2013
1EnkephalinsIBA
06/2012
1Ala(2)-MePhe(4)-Gly(5)- Enkephalin (DAGO)IBA
06/2012
1Opioid Analgesics (Opioids)IBA
06/2012
1Pharmaceutical PreparationsIBA
04/2012
1Interleukin-7 (Interleukin 7)IBA
01/2012
1aerolysinIBA
10/2011
1Triglycerides (Triacylglycerol)IBA
07/2011
1AMP-Activated Protein KinasesIBA
07/2011
1Peptides (Polypeptides)IBA
02/2011
1L-Lactate Dehydrogenase (Lactate Dehydrogenase)IBA
02/2011
1BerberineIBA
12/2010

Therapy/Procedure

4Lasers (Laser)
04/2022 - 11/2008
3Therapeutics
08/2019 - 02/2011
3Ileostomy
10/2009 - 08/2006
2Colectomy
10/2009 - 08/2006
1Capsulorhexis
04/2022
1Ligation
01/2019
1Gluten-Free Diet
07/2012